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Spatial statistical modelling of epigenomic variability

 

Andreas Kapourani

I am interested in developing statistical models to understand (single-cell) epigenetic heterogeneity and capture spatial  correlations of epigenetic marks that would uncover the interplay  between genetic and epigenetic mechanisms in transcriptional  regulation. Also, I am interested in probabilistic integrative models  for combining multimodal biological data, such as expression,  methylation and accessibility

 

Supervisors: Guido Sanguinetti & Duncan Sproul